Medical Health Care Advices

Ovarian Cancer  A U.S. clinical study showed that the combination treatment (Avastin) and chemotherapy significantly slows the progression of ovarian cancer. Dr. Robert Burger of Fox Chase Cancer Center in Philadelphia (Pennsylvania East), who led the research, explained that this Phase 3 clinical trial, the first of its kind, has shown that blocking the formation of tumor and blood vessels significantly improves survival without disease progression in women with ovarian cancer or peritoneal very difficult to treat.
“The results of this trial showed that Avastin is an acceptable initial treatment for patients suffering from advanced ovarian cancer,” he said in presenting the results at the annual conference of the American Society of Clinical Oncology (AUC0) meeting this weekend in Chicago (Illinois, North).

Small clinical trials with Avastin had previously already shown encouraging results in women with ovarian or peritoneal cancer recurring. This international clinical trial has focused on 1,873 women recently diagnosed with advanced cancer (stage 3 and 4) ovarian, peritoneal and tubes fallopiens who underwent surgery to remove the largest possible part of the tumor. These patients were divided into three groups. In the first, women were treated with standard chemotherapy (paclitaxel combined with carboplatin) plus placebo. In the second, she received the same chemotherapy over Avastin. In the third group, patients were also treated with chemotherapy plus Avastin but with the one followed by ten months with Avastin alone. The latter group had a survival of 14 months (median) compared with 10 months for those who have had chemotherapy, a statistically significant difference, say the authors of the research. Ovarian cancer is the sixth largest in the world order of frequency among the gynecological cancers and affects 230,000 women each year, nearly 140,000 die. This is the eighth cause of cancer deaths among women.

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