Amyloidosis
Amyloidosis is a disease characterized by the accumulation in tissues and organs of an abnormal protein called amyloid. Protein deposits can be made in a single organ or dispersed throughout the body.
The disease causes serious problems in the affected areas, such as the heart, brain, kidneys and digestive tract. As a result, people with amyloidosis in different parts of the body can experience different physical problems:
* Brain: Dementia
* Heart: heart failure, arrhythmias, enlarged heart
* Kidneys: renal
* Nervous system: numbness, tingling or weakness
* Digestive System: gastrointestinal bleeding, intestinal obstruction, malabsorption of nutrients
* Blood: low blood count, easy bruising or bleeding
* Pancreas: Diabetes
The causes of amyloidosis. Amyloidosis is not a single disease may be involved different types of amyloid proteins. For example, Alzheimer’s disease and Creutzfeldt-Jakob disease (a rare cause of dementia associated with viruses that live in cattle) are two different conditions that are characterized by deposits of amyloid in the brain, but the proteins involved are different .
Amyloidosis is classified as primary or secondary. When there is no underlying disease and the main problem is caused by amyloidosis, the disorder is considered primary. When another disease, usually a chronic inflammatory condition such as tuberculosis and rheumatic disease, causes amyloidosis, the disorder is considered secondary.