Antibody
The Complement System for Antibody Action
The complement system for antibody action. Complement is a system of nine different enzyme precursors (designated Cl to C9) which is normally found in plasma and other body fluids, but are also normally inactive enzymes. However, when an antibody combines with an antigen, antigen becomes the complement system activator. Just a few combination to activate antigen large number of enzyme precursor molecules in the first stage of the complement system, activated enzymes thus formed then many more enzymes in the later stages of the system. The activated enzymes then attack the invaders in various ways, initiate local tissue reactions, and provide protection against injury by the invader. Among the most important effects that occur are the following:
1. Lysis. Proteolytic enzymes digest the complement system portions of the cell membrane, thus disrupting cellular agents such as bacteria or other invading cells. Read the rest of this entry »