Small clinical trials with Avastin had previously already shown encouraging results in women with ovarian or peritoneal cancer recurring. This international clinical trial has focused on 1,873 women recently diagnosed with advanced cancer (stage 3 and 4) ovarian, peritoneal and tubes fallopiens who underwent surgery to remove the largest possible part of the tumor. These patients were divided into three groups. In the first, women were treated with standard chemotherapy (paclitaxel combined with carboplatin) plus placebo. In the second, she received the same chemotherapy over Avastin. In the third group, patients were also treated with chemotherapy plus Avastin but with the one followed by ten months with Avastin alone. The latter group had a survival of 14 months (median) compared with 10 months for those who have had chemotherapy, a statistically significant difference, say the authors of the research. Ovarian cancer is the sixth largest in the world order of frequency among the gynecological cancers and affects 230,000 women each year, nearly 140,000 die. This is the eighth cause of cancer deaths among women.

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Tumors arising in the ovaries are, in most cases, benign but some are truly malignant, cystic or solid form, originating from cells undergoing malignant transformation and grow in a disorderly and uncontrolled can invade and destroy nearby tissues.

Ovarian cancer causes more deaths than any other type of gynecologic cancer and accounts for 5% of cancer deaths among women. It is estimated that about 2% of women suffer from ovarian cancer at some point in their lives.

There are different types of ovarian tumors, depending on the cell from which they originate. In most cases, approximately 80% are derived from epithelial cells. The rest originates from cells called germ cells or reproductive and serving as a supporting structure of the organ.

Ovarian cancer, producing clinical manifestations in advanced stages, early detection is difficult. A study of the blood, which verified the levels of a tumor marker, CA-125, which in some cases it is useful to detect early. While it is important to consider that this analysis is not performed routinely but should take into account the presence of risk factors to apply.

In recent years, with the advent of transvaginal ultrasound, in which a small instrument is inserted into the vagina, has been detected in an earlier many of these tumors, to observe more closely the female sexual organs.

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